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The best candidates are people who see the medication as a tool for finally getting traction on: Higher protein intake Regular strength training to preserve muscle A sustainable eating pattern they can keep when they are not on medication If youre hoping to take the medication and change nothing else, you will probably lose weight, but you will also likely regain it

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For example, a novel dual agonist of GLP-1/GIP receptors significantly increased BDNF levels in a mouse model of Parkinsons disease, induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration [53]