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A weekly subcutaneous injection is sufficient to deliver the anti-miR without loss of activity

Common reported side effects: Gastrointestinal effects are the most frequently reported side effects across published GLP-1 clinical trials and FDA labeling, including nausea, vomiting, diarrhea, constipation, abdominal pain, decreased appetite, and acid reflux

Report these symptoms to your healthcare provider immediately, and seek emergency care for severe uncontrolled bleeding or signs of stroke

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The doses used in trials were around 500ug/kg, which means a 100kg person was receiving 50mg of the peptide daily. $50 million in research and development down the drain for a promising product that was no longer a viable pharmaceutical product

Hekler, A