This is likely due to the existence of intracellular GSH transporters and of some alternative back-up reducing systems
however, in the case of injury or disease, loss of NMNAT activity leads to NAD + depletion and NMN accumulation, which in turn activates SARM1 53,54,289
Fortunately, advances in pharmaceutical compounding now offer patients and practitioners an alternative: Cyanocobalamin combined with Salcaprozate Sodium (SNAC) , an oral formulation shown to be comparable to traditional intramuscular (IM) injections
Its potential as an anti-cancer drug is yet to be explored, but results from research so far look promising
Similarly, a study using diffusion tensor imaging to assess white matter microstructure in pediatric concussion also failed to find differences in white matter microstructure at 11 days following injury 12 , although another study found higher mean diffusivity in the thalamic radiation 3 months post-injury and reductions in mean diffusivity of the arcuate fasciculus at 6 months post-injury 13
From protecting your cells and boosting your immune system to supporting liver detox and even brightening skin, its benefits are far-reaching