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Factors that Affect How Long Vitamin B12 Shots Stay In the Body No Vitamin B12 Deficiency If you dont have a vitamin B12 deficiency, most of the vitamin B12 you get through your injection will be absorbed and eliminated quickly through your urine

Due to the limited data, it should be avoided by anyone who is pregnant, breastfeeding, or undergoing active cancer treatment

However, none of the studies reported on hematological or clinical outcomes

The Cleveland Clinic notes that bariatric surgery patients are at increased risk for vitamin deficiencies and often require ongoing supplementation: Individuals Using GLP-1 Medications GLP-1 receptor agonists (such as semaglutide and tirzepatide) are commonly used for metabolic health and weight management

Metformin, a drug used to treat type 2 diabetes, can also decrease absorption of B12 in the small intestine of 10 percent to 30 percent of patients

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