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Inhibition of the acetyl-CoA carboxylase suppresses the de novo lipogenesis and improves fatty acids oxidation (37, 40)

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Prescribed since 2005 for the treatment of Type 2 diabetes mellitus, the drugs more recently gained weight loss indications

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Sulforaphane regulates cell proliferation and induces apoptotic cell death mediated by ROS-cell cycle arrest in pancreatic cancer cells