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Findings include changes in satiety signaling, alterations in feeding rhythms, reduced food-seeking behavior, and modulated glucose-response patterns in research subjects

The cytoprotective role of the Keap1-Nrf2 pathway

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and cognitive impairments, which involve deficits in attention, working memory, and executive functions critical for goal-directed behavior (van Os and Kapur, 2009)

Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those using diuretics concomitantly and the elderly