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------------------------------------- Niacinamide (Vitamin B3): Niacinamide is the water soluble form of niacin, an essential vitamin for healthy cell metabolism and is part of the B group

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Furthermore, apart from the established impact of cutaneous irAEs on OS of melanoma patients, gastrointestinal irAEs, especially diarrhoea, which usually limits ICI treatment, was paradoxically associated with improved OS and PFS in metastatic melanoma patients (HR 0.56

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