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Upon centrifugation (3000 rpm for 10 min) at 4C, the resulting supernatants were obtained for ELISA assessment of IL-1 , IL-6 and TNF- with specific kits (Reference Hammitzsch, Chen and de Wit22,Reference Sexton, Hachem and Assi23)

Some regions showed lymphoepithelial lesions (LELs) and germinal centre (GC)-like structures

CBF delivers the necessary oxygen and nutrients to the brain cells, and its regulation is dynamically adjusted according to the metabolic needs of the neurons