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Neuroinflammation in aging is characterized by the accumulation of many cytokines, in which the most obvious change is IL-2 production 64

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The charge transfer from BSA/AuNCs to FA-rGO weakens the AuS bond between cysteine residues and the Au core, which in turn reduces charge transfer from BSA ligands to AuNCs, leading to the fluorescence quenching of AuNCs

Therefore, direct support for Th1 and NK cell activity should be considered especially in patients over 70 years old