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For example, a caudatin-cinnamic acid hybrid could suppress HBV DNA replication (IC 50 = 2.44 M) by inhibiting the activity of the HBV X promoter (Xp) and enhancer I (ENI), which are critical for viral gene expression (Table 1, Row 20)
Maintenance doses can be adjusted based on UV exposure: higher doses (1mg twice weekly) during months with minimal sun exposure, lower doses (0.5mg twice weekly) during summer or periods of frequent outdoor activity
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Epigenetics in platelet hyperactivity Epigenetic changes may influence the generation and release into the circulation of proteins involved in blood coagulation and fibrinolysis
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