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doi: 10.1210/clinem/dgaa951 85 HaLXWuYYYinTYuanYYDuYD

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The closing of the extracellular regions by the ECD and the reorganization of the TMD conformation interfere with the binding of GLP-1 to the orthosteric pocket in the inactive state of full-length GLP-1R (Supplementary Fig

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