If discontinuation is necessary, our guide to stopping Ozempic and managing weight regain provides strategies, though maintaining treatment through affordable alternatives is preferable if possible
Worsening depression, behavior changes, or suicidality
Third, the study is unique in also using validated questionnaires for mental disorders common in obesity and T2D to standardise the baseline mental health characteristics of the participants and attempt to substantiate and further interpret the subjective experience of change in mental health with change in scores
Start with one compound (typically Tirzepatide), titrate to your target dose, and stabilize before adding MOTS-c
Yunfeng Liu, [email protected] These authors have contributed equally to this work and share first authorship These authors have contributed equally to this work This article was submitted to Clinical Diabetes, a section of the journal Frontiers in Endocrinology ORCID: Yi Zhang, orcid.org/0000-0003-0305-3127 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Thirty randomly selected participants from the parent LIRAFLAME trial underwent paired [Cu]Cu-DOTATATE PET/CT imaging of the coronary arteries at baseline and after 26 weeks