doi: 10.3389/fpubh.2022.996179 Received 17 July 2022 Accepted 30 September 2022 Published 20 October 2022 Volume 10 - 2022 Edited by ke Sjholm, Gvle Hospital, Sweden Reviewed by Hao Li, Shanghai Jiao Tong University, China
When to Expect Results Typical patient timeline: Improved glow & hydration: 24 weeks Skin tightening & texture improvement: 48 weeks Hair growth stimulation: 612 weeks Maximal collagen remodeling: 12+ weeks Deep regenerative benefits: ~90 days GHK-Cu delivers both immediate cosmetic benefits and long-term cellular repair
The HSE doesnt cover it under the Drug Payment Scheme yet theyre still deciding if its value for money. Still not pocket change, but considerably less painful
I see a lot of anecdotal reports of anhedonia and I suspect if a patient already has issues with their dopaminergic system, reward motivation, etc, that they might not be the best candidates for GLP-1 agonists for depression treatment as they can cause anhedonia even in low doses by affecting brain reward pathways and blunting dopamine signaling, often reported as emotional flatness
Limited data are available on the use of vitamins for symptomatic relieve in ME/CFS patients
2.2 Study screening Meta-analyses and systematic reviews that reported the effects of GLP-1RAs on MASLD were included