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The expression of genes for a series of antioxidant-related enzymes (-glutamylcysteine synthetase, GSH reductase, glutathione- S -transferase, GSH peroxidase, and superoxide dismutase) in diverse tissues was upregulated by these supplements [35]

It also indicated directional differences between symptomatic patients and asymptomatic V30M carriers ( p = 0.0297), as well as between asymptomatic V30M carriers and healthy controls ( p = 0.0477

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Because an analog is not identical to the naturally occurring peptide, early-phase trials primarily assess safety rather than proving long-term effectiveness