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The occurrence of abnormal biomarkers indicating mitochondrial dysfunction is more common in patients with ASD than in the general population

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Loss of Potency: This is harder to spot without advanced testing, but it can occur from improper storage (e.g., exposure to heat or light), repeated freeze-thaw cycles, or using non-bacteriostatic water for extended storage

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Acknowledgements David Wright, Copy Editor

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1 Introduction Kidney disease is a major global non-communicable disease (NCD), with a global prevalence exceeding 10% [affecting ~850 million people when including acute kidney injury (AKI), kidney failure, and dialysis/transplant recipients] ( Cell death is a finely regulated process that occurs through various molecular pathways ( Recent studies have confirmed that the kidney is particularly susceptible to redox imbalance, and ferroptosis plays a significant role in the pathophysiology of various kidney diseases, emerging as a new research hotspot in the field of renal fibrosis ( Figure 1

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