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In particular, dysregulation of the gut-liver-muscle-brain axis, driven by hyperammonemia, systemic inflammation, sarcopenia, altered bile acid signaling, and gut dysbiosis, plays an important role in the pathogenesis and progression of CHE [9, 10]
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Therefore, the conceptual evidence can be summarized as follows (Figure 1)
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Food systems are increasingly recognized as major contributors to global anthropogenic greenhouse gas emissions, with food production alone responsible for approximately one-third of global emissions (IPES Food, 2016
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