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Nausea-related discontinuations occurred at higher doses

Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP 1) - Wilding JPH et al., NEJM 2021 68-week phase-3 Wegovy registration trial

The most common side effects of Wegovy are gastrointestinal, including nausea (44% of patients), diarrhoea (30%), vomiting (24%), constipation (24%), and abdominal pain (20%)

Fasting glucose and HbA1c levels are essential baselines, especially since semaglutide significantly improves glycemic control

This can affect the digestion and absorption of dietary fats and fat-soluble vitamins (A, D, E, K), but does not impact the injectable medication itself

Examples of questions you may want to ask your doctor include: If I have high blood pressure, would Ozempic or Mounjaro be a better option for me