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Recent data demonstrate that acute central administration of 5 g of the centrally selective TGR5 agonist, 3-(2-chlorophenyl)-N-(4-chlorophenyl)-N,5-dimethyl-4-isoxazolecarboxamide, significantly reduces body weight gain in mice
Particles can come from: Degraded peptide forming insoluble aggregates Contamination during manufacturing or storage Rubber stopper fragments from repeated needle punctures Crystallization of dissolved components If you see particles, do not try to filter them out
Bloodwork beats body weight
A 57-year-old woman with a BMI of 45.5 and prior breast cancer developed an occlusive DVT of her left subclavian vein after eight months on tirzepatide 10 mg weekly (tirzepatide is a dual GLP-1/GIP agonist)
Furthermore, this drug also exhibited a reduced risk of myocardial infarction, ischemic stroke, and hemorrhagic stroke
All samples were created and analysed in triplicate
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