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McBean G (2017) Cysteine, glutathione, and thiol redox balance in astrocytes

Furthermore, vagotomy can abrogate other metabolic and neurotransmitter signals from the gut to the brain, including SCFAs, BDNF, and GABA, demonstrating that the vagus nerve is required for gut-to-brain metabolic signaling [261, 266, 271, 272]

Microbiota-derived metabolites are key mediators of host-microbe interactions ( 2.3 Bidirectional neuroendocrine crosstalk In addition to regulating host metabolism and immune responses, the gut microbiota is recognized to play a critical role in the production of neurotransmitters and engages in complex bidirectional communication with the hypothalamicpituitarygonadal (HPG) axis, contributing significantly to the pathogenesis and potential treatment of PCOS

Creatine also improves cognition and significantly decreases headaches, dizziness and fatigue after a concussion