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Saxenda also works best when combined with a nutritious diet and regular exercise

This momentum in drug development for MASH underscores a growing need for translatable preclinical models that accurately reflect human MASH pathology, support mechanistic insights, and predict treatment responses for streamlining the transition from preclinical to clinical development

Patients with a history of medullary thyroid carcinoma, pancreatitis, or severe gastrointestinal disease should avoid these medications

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The rare but serious side effects identified in trials include pancreatitis (0.3%), gallbladder events (1.4%), and acute kidney injury (0.7%)