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When the body metabolises fat stores quickly, there can be changes in urinary composition, including increased uric acid excretion and alterations in urinary pH

Some individuals may respond more favorably than others, necessitating adjustments to the treatment duration

Nature 421:753756 del Pozo MA, Price LS, Alderson NB, Ren XD, Schwartz MA (2000) Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK

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