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Like the ADA, the AACE/ACE algorithm recommends intensification from monotherapy to dual therapy and beyond for patients not achieving glycemic goals after 3 months of therapy with a given antihyperglycemic regimen

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10.1080/03008207.2019.1665035 Summary Keywords knee osteoarthritis, oxidative stress, reactive oxygen species, cartilage, synovitis Citation Liu L, Luo P, Yang M, Wang J, Hou W and Xu P (2022) The role of oxidative stress in the development of knee osteoarthritis: A comprehensive research review

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