Data availability The datasets generated in this study, including previously published RNA sequencing raw data, are available in the Mendeley Data repository ( with DOI: 10.17632/5hd3f79d6m.1
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Gastrointestinal adaptation timeline Beyond nausea, other gastrointestinal effects follow their own timelines: Diarrhea affects some users and typically appears during dose escalation periods
Male infertility: decreased levels of selenium, zinc and antioxidants
Jenab Y, Sadeghipour P, Mohseni-Badalabadi R, Kaviani R, Hosseini K, Pasebani Y, Khederlou H, Rafati A, Mohammadi Z, Jamalkhani S, Talasaz A, Firouzi A, Ariannejad H, Alemzadeh-Ansari M, Ahmadi-Renani S, Maadani M, Farrashi M, Bakhshandeh H, Piazza G, Krumholz H , Mehran R, Lip G, Bikdeli B
Together, they outline a personalized pathway for the patient and determine the required analyses