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Autoimmune Conditions Commonly Associated With Chronic Pain Many autoimmune and inflammatory disorders can contribute to persistent pain, including: Rheumatoid arthritis Psoriatic arthritis Lupus Hashimotos thyroiditis Sjogrens syndrome Inflammatory bowel disease Small fiber neuropathy Fibromyalgia-like inflammatory syndromes Undifferentiated connective tissue disease The Role of Neuroinflammation in Chronic Pain One of the most important emerging concepts in pain medicine is the role of neuroinflammation
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[5] Administering 100,000 IU intramuscularly establishes a high-capacity depot that may correct deficiency more predictably than oral dosing in malabsorption syndromes and maintains adequate circulating vitamin D over two to three months, an approach often referred to as Stoss therapy in endocrinology