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Constipation, which occurs in approximately 525% of patients depending on the specific product and dose, may cause lower back discomfort

Collectively, our data suggest that injected fibroblasts can induce NP cells to adopt a fibroblastic phenotype via the TGF/Smad signaling pathway, leading to reparative fibrosis of the IVD, which helps to suppress further degeneration of the intervertebral disc

Whether you are starting semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound), the initial weeks bring noticeable changes, some exciting and some uncomfortable

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These drugs should only be prescribed by healthcare professionals alongside continued care and advice on diet and activity

It is important to know the difference between a manageable side effect and a serious medical concern