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10.1016/j.freeradbiomed.2015.05.036 Free Radic Biol Med
However, it was found that estrogen did not inhibit reactive oxygen species(ROS)
This anti-inflammatory and cardioprotective profile has led some researchers to suggest that GLP-1 agonists are not just weight loss drugs, they are metabolic therapies with wide-ranging systemic benefits
While 0.5 mg is an FDA-approved maintenance dose for type 2 diabetes, many patients require 1 mg or 2 mg weekly for optimal glycemic control
Post hoc evaluations of the SUSTAIN 6 trial revealed that semaglutide markedly increased the incidence of diabetic retinopathy complications in individuals with a history of retinopathy, especially among insulin users, presumably due to the swift deterioration of pre-existing retinopathy following rapid glycemic control [91]
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