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It is a regulatory safety evaluation, not a drug approval hearing

PAGln was identified through untargeted metabolomic analysis in a large-scale clinical study to be increased in circulation and associated with CV-related disease and major adverse cardiovascular events (i.e., stroke, myocardial infarction, and death) 11

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These consequences may, in turn, increase healthcare utilization and associated costs through additional diagnostic testing, clinic visits, or hospitalizations

/ If you were using it for skin tone, be extra diligent with sunscreen