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Pentadeca-Arginate (PDA) is a synthetic peptide with the same number of amino acids as BPC-157, but with a critical difference: it includes an arginine modification that makes it far more stable in acidic environments
1 Mecobalamin 50 mg or placebo was administered intramuscularly twice weekly for 16 weeks to 130 ALS patients who had suffered from ALS for less than one year, were classified as definite, probable, or probable-laboratory supported according to the Updated Awaji Criteria, had an ALS severity rating of grade 1 or 2, had a decrease of 1 or 2 points in the total score on the Revised ALS Functional Rating Scale-Revised (ALSFRS-R) 12 weeks prior to administration, and had a forced vital capacity (%FVC) of more than 60%
A peptide is a short chain of amino acidsessentially a fragment of a protein
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The studies below cover the key findings for each compound individually