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Treatment with all uric acid concentrations caused a significant increase in protein carbonyl levels at 1 h compared with those in the control group, but 10 mg/dl uric acid dose resulted in a reduction compared with the other doses (2.5, 5 and 25 mg/dl uric acid) (Fig
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In severely ill patients in septic shock, muscle biopsies have shown an association between mitochondrial dysfunction, as assessed by levels of reduced glutathione, and mortality [12]
Published online August 12, 2025