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High-risk groups include older adults, vegans, individuals with pernicious anaemia, those with malabsorption conditions such as Crohn's disease or coeliac disease, people taking metformin or proton pump inhibitors long-term, and those with recent nitrous oxide exposure including recreational use
Mounjaro is a diabetes medication that improves blood sugar, while Zepbound is used for chronic weight management
10.1016/j.jneuroim.2015.10.001 95
Melanocortin Agonist: Contains PT141, which acts on receptors in the central nervous system
Fat, protein, and fiber all reduce oral semaglutide bioavailability, so waiting 30 minutes after dosing before eating is essential
However, adverse effects included fatigue, insomnia, and small increases in fasting glucose and insulin resistance
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