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Randomized, double-blind human trials have shown that GHK-Cu application produces a 55.8% reduction in wrinkle volume and a 32.8% reduction in wrinkle depth compared to controls over 8 weeks

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However, efficacy varies markedly by strain, formulation, dosing regimen, host characteristics, and disease activity, and not all probiotic products are effective

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This formulation is designed to provide patients with a convenient and effective way to consume this vital antioxidant

Randomized trials need to be designed to test that hypothesis directly, not inadvertently suppress it through exclusion criteria