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In terms of safety, Semaglutide has a favorable profile but does carry risks, including gastrointestinal upset, a potential link to thyroid C-cell tumors in rodent studies, contraindication in Multiple Endocrine Neoplasia syndrome type 2, and risks of acute and chronic pancreatitis

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Furthermore, they also found that 'a balanced dual agonist in mice engineered to lack GLP-1 receptors still induced weight loss, proving that the compounds were not causing weight loss purely by targeting GLP-1' (Molteni, Chen)

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These observed effects of DMSO could also be due to a single or combination of its following biological enhancing properties