Age, genetics, and existing health status all affect conversion rates
Given levothyroxine's narrow therapeutic index, thyroid function should be reassessed 6-8 weeks after significant weight loss or if persistent gastrointestinal symptoms develop
It should be used with caution in pediatric patients, particularly those younger than 1 month old, due to limited safety data in this population
Rossing P, Baeres FMM, Bakris G et al (2023) The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease
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Multiple studies confirm this