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The most common event type leading to discontinuation was gastrointestinal adverse reactions reported in 3.4% with Wegovy pill and 2% with placebo

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The potential value of combining these therapies lies in addressing overlapping cardiorenal and metabolic risk pathways as available evidence for dual therapy in HF populations remains limited and is derived largely from subgroup analyses, observational studies, and extrapolation from diabetes or obesity trials rather than dedicated HF randomized trials [24, 25, 27, 30, 50]

Jerry RG, Jeffrey WM, Julia MK, Elana H, Julie HS, Gregory SC, et al

Long-chain Acyl-CoA synthetase 4-mediated fatty acid metabolism sustains androgen receptor pathway-independent prostate cancer