Annual Review of Biochem
Together, molecular clocks, neural circuits, and hormonal signals form an integrated neuroendocrinecircadian axis that coordinates physiological homeostasis and modulates stress responses
[1] The most common cause is certain medications such as lamotrigine, carbamazepine, allopurinol, sulfonamide antibiotics and nevirapine
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ACKNOWLEDGEMENT The authors declare no conflict of interest relevant to this article
Abnormal estrogen signaling through ER is a major driver of tumorigenesis in luminal A and luminal B breast cancers [4], as it promotes the proliferation of cancer cells by overexpressing cyclin D1 and c-Myc, both of which enable the tumors to bypass the G1/S checkpoint [5]