Thioredoxin reductase and glutathione reductase Thioredoxin reductases (TrxRs) are enzymes that use electrons from NADPH + H + to restore the active reduced state of oxidized Trx (Fig
In: Schattman GL, Esteves SC, Agarwal A, editors
Antidepressant monotherapy is not recommended to treat bipolar depression [7, 13], highlighting the need to understand the biological mechanisms specific to bipolar depression
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