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Both forms work as glucagon-like peptide-1 (GLP-1) receptor agonists, signaling satiety pathways in the brain and slowing gastric emptying

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In Studies 1 and 2, patients were randomized to 1 of 4 treatment groups: RYALTRIS 2 sprays (665 mcg olopatadine hydrochloride and 25 mcg mometasone furoate per spray) per nostril twice daily, olopatadine hydrochloride nasal spray 2 sprays (665 mcg per spray) per nostril twice daily, mometasone furoate nasal spray 2 sprays (25 mcg per spray) per nostril twice daily, and vehicle placebo for 2 weeks