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Further research is necessary to fully characterize its mechanisms of action and broader applications within biomedical science
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With sufficient glutathione present, NAPQI is very quickly metabolized into sulfate and cysteine compounds, which are readily excreted through the kidneys.[ref] However, when it isnt neutralized, NAPQI is highly reactive and can cause oxidative stress and damage to the liver cells, hepatocytes, leading to cell death
During the treatment, no significant increase in glutathione (GSH) was observed [11]
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