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Fumarate, one of the intermediates of the TCA cycle, is considered to be an oncometabolite that promotes cancer based on the human cases carrying heterozygous germline mutations in the fumarate hydratase ( FH ) gene

Uncovering the trimethylamine-producing bacteria of the human gut microbiota

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We have screened a number of TGR inhibitors and identified potential lead compounds for novel drug development

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