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Stimulating insulin and blocking glucagon

(2) Jastreboff AM, et al

146: 2625S2629S, doi: Stragier S, Baudry S, Poortmans J, Duchateau J, Carpentier A

The appetite-suppressive effects create a secondary concern: patients taking both drugs may inadvertently restrict calories to unsafe levels, leading to nutrient deficiencies, muscle loss, or metabolic adaptation that undermines long-term weight loss

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It is produced through solid-phase peptide synthesis and supplied as a sterile, lyophilized powder for stable storage and consistent laboratory handling