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One of them is GSK-3, a Ser/Thr protein kinase involved in several metabolic processes, including glycogen metabolism and insulin signalling [213]

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Tirzepatide (Mounjaro/Zepbound) is a dual GIP/GLP-1 receptor agonist that has shown even greater weight loss than semaglutide in head-to-head trials

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doi: 10.1194/jlr.C600019-JLR200 38 HosnedlovaB.KepinskaM.SkalickovaS.FernandezC.Ruttkay-NedeckyB.PengQ.et al