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By extending earlier preclinical work on GLP-1 receptor agonists and alcohol intake to a task that directly assesses the subjective effects of alcohol, these findings provide important context for interpreting clinical observations of reduced drinking behavior among individuals receiving GLP-1 receptor agonist-based therapies

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The study's findings showed that in immunocompetent mice bearing experimental melanoma, SPIONs containing 5-FU demonstrated increased skin penetration as well as enhanced tumor development retardation when compared to Doxorubicin