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Each workout produces an acute burst of reactive oxygen species (ROS) in muscle, which paradoxically triggers the cell's defense mechanisms a phenomenon known as mitohormesis ( 3.3 Physical capacity and metabolic health The systemic benefits of exercise in older adults extend to muscle strength, endurance, and metabolism

Anyone with cardiovascular conditions, orthopedic limitations, or a history of significant metabolic disruption should obtain physician clearance before beginning a progressive resistance program

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