This volume reduction is more pronounced in patients with multiple episodes, recurrent relapses, and longer disease duration ( postmortem brain tissue from patients with MDD and found diminished glial cell density and neuronal volume in the dorsolateral PFC
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[DOI] [PMC free article] [PubMed] [Google Scholar] Schifitto G, Yiannoutsos CT, Ernst T, Navia BA, Nath A, Sacktor N, Anderson C, Marra CM, Clifford DB