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Ive just been really constipated, she said

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Although PSD patients generally tolerate these treatments well, clinicians must consider individual characteristics, potential drug interactions (e.g., with anticoagulants), and side effects (e.g., the anticholinergic effects of TCAs and the influence of SNRIs on blood pressure), which may significantly affect outcomes (Yuan et al., 2023)

However, theres an important caveat: most of the data comes from animal research, not human clinical trials