The catalytic subunit of GCL is subject to competitive feedback inhibition by glutathione, thus preventing an excess of glutathione production (Richman and Meister 1975)
The peptides molecular structure prevents it from crossing the blood-brain barrier and accessing hypothalamic regions responsible for hunger signaling, satiety, and feeding behavior
Alongside these pathways it influences growth-factor signalling, collagen synthesis and fibroblast activity, the building blocks of soft-tissue repair
Collagen density increases, fine lines soften, skin thickness measurably increases
Individuals experiencing any adverse symptoms following use of an unlicensed compound should seek urgent medical attention and inform their clinician of all substances taken
For this reason, optimal blood levels of pregnenolone are critical for a healthy hormone balance