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Nighttime Dosing: Others find that taking GLP-1s at night allows them to sleep through the nausea, effectively avoiding the discomfort

Temperature requirements Compounded semaglutide should be stored in the refrigerator at 36-46 degrees Fahrenheit (2-8 degrees Celsius)

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Their overall claim: Results from the STEP UP trial therefore support a favourable benefit-risk profile of semaglutide 7 2 mg for weight management in people with ob*sity, and suggest that a higher dose of semaglutide up to 7 2 mg per week could be used to achieve greater clinical benefits in people not reaching therapeutic goals with once-weekly semaglutide 2 4 mg

This recommendation is based on stability data and microbiological safety considerations, as the sterility of the solution cannot be guaranteed beyond this period once the seal has been broken

People with severe gastrointestinal issues that could worsen with slowed digestion