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6ac show that the expression of chondrogenic genes ( ACAN , COL II , and SOX9 ) in the joint tissue mediated by PTK hydrogel was 59.7, 13.3, and 4.7 times higher than that in the control group, which was also significantly higher than that in the PMI treated group

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At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues

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Its primary role is to deliver essential trace minerals, specifically copper ions, to cells

2021;320(3):C375-C391