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Future studies should focus on refining experimental models, integrating multi-omics approaches, and establishing standardized assessment systems to enhance the clinical relevance of preclinical findings and facilitate the translation of novel therapeutic strategies into practice

[7] The relevance of these animal findings to human patients remains uncertain and is the subject of ongoing pharmacovigilance

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Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats

However, the FDA mandated a boxed warning stating that the discontinuation of the therapy may result in severe acute exacerbations of hepatitis B and that hepatic function should be monitored closely

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