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doi: 10.1016/j.toxlet.2007.02.013 221 DickinsonAYeungKDonoghueJBakerMKellyRDMcKenzieMet al

However, a growing body of evidence suggests that it also affects food intake and body weight (2325)

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Furthermore, gut microbiota modulates the bioavailability, absorption, and metabolism of essential micronutrients required for thyroid hormone biosynthesis

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Side note: I say earlier because research shows that many people with symptomatic osteoarthritis follow a delayed-response trajectory, where meaningful improvements dont appear until the 812 week mark